Table 1.

Effect of an O. ostertagi on transcript levels of signaling network components involved in gastric cell homeostasis (mean fold difference compared to uninfected calves ± SEM)

	Single infection			Trickle infection
	Experimental			Experimental	Natural
Gene	6 dpi	9 dpi	24 dpi	60 dpi	60 dpe
HB-EGF	2.61 ± 1.3	4.47 ± 0.68*	7.12 ± 1.33*	6.45 ± 1.11**	5.13 ± 1.31*
AREG	3.57 ± 1.78*	4.01 ± 0.82*	11.40 ± 1.58*	7.79 ± 0.77**	8.86 ± 2.48*
FGF10	2 ± 0.2	2.34 ± 0.43	4.33 ± 0.45*	1.83 ± 0.13**	2.58 ± 0.46*
HES1	1.79 ± 0.24*	2.07 ± 0.34*	2.3 ± 0.3*	3.20 ± 0.36**	1.97 ± 0.2*
ADAM10	1.66 ± 0.83*	2.44 ± 0.6*	2.64 ± 0.68*	1.76 ± 0.19	2.14 ± 0.22*
ADAM17	1.96 ± 0.25*	2.16 ± 0.29*	3.5 ± 0.6*	2.41 ± 0.25**	2.66 ± 0.26*
Wnt5A	1.93 ± 0.17*	1.92 ± 0.31*	3.09 ± 0.22*	2.76 ± 0.30**	2.01 ± 0.31*
SHH	2.25 ± 0.68	2.26 ± 1.06	1.98 ± 0.49	2.93 ± 0.61**	1.81 ± 0.44
BMP4	1.31 ± 0.16	1.7 ± 0.36	1.63 ± 0.14	1.69 ± 0.15	1.26 ± 0.09
FGF20	2.27 ± 0.33	2.87 ± 1.78	1.95 ± 0.31	1.44 ± 0.26	2.94 ± 0.31*
GIF	1.7 ± 0.22	1.13 ± 0.05	0.85 ± 0.15	0.61 ± 0.01**	0.72 ± 0.15

*p value ≤ 0.05 uninfected animals vs infected animals.

**p value ≤ 0.01 uninfected animals vs infected animals.