Table 3.
Effect of an O. ostertagi on transcript levels of inflammatory-related genes (Mean fold difference compared to uninfected calves ± SEM)
|
Single infection |
Trickle infection |
|||
---|---|---|---|---|---|
|
Experimental |
Experimental |
Natural |
||
Gene | 6 dpi | 9 dpi | 24 dpi | 60 dpi | 60 dpe |
IL1B |
3.01 ± 1.29 |
5.96 ± 0.84* |
35.37 ± 10.77* |
3.52 ± 0.49* |
5.51 ± 1.86 |
IL8 |
3.11 ± 1.8 |
5.52 ± 1.6* |
50.68 ± 14* |
8.53 ± 1.55** |
9.65 ± 2.66* |
TNFA |
1.81 ± 0.41 |
2.02 ± 0.31 |
5.44 ± 1.32 |
2.20 ± 0.0381* |
3.76 ± 1.06 |
COX-2 | 1.05 ± 0.1 | 1.65 ± 0.2 | 6.45 ± 1.67* | 2.92 ± 0.36** | 1.69 ± 0.22 |
*p value ≤ 0.05 uninfected animals vs infected animals.
**p value ≤ 0.01 uninfected animals vs infected animals.