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. 2004 May;72(5):2507–2512. doi: 10.1128/IAI.72.5.2507-2512.2004

FIG. 1.

FIG. 1.

Hexavalent protein-specific antibody titers in sera from mice immunized i.n. with formulations of hexavalent protein containing liposomes and lipid A (H/L/MPL) or liposomes only (H/L) (A), CT-B with or without holotoxin (H/CT-B/CT or H/CT-B, respectively) (B), or proteosomes (H/Pr/LPS) (C). Specific antibody titers for control mice that received only liposomes (L), CT-B/CT, or proteosomes (Pr/LPS), respectively, are also indicated (titers < 100). Each bar represents the mean (± standard error of the mean) antibody titer in serum from 10 mice in each group 2 weeks after the final immunization. *, P < 0.05 for H/L/MPL versus H/L and versus L, for H/CT-B/CT versus CT-B/CT, and for H/Pr/LPS versus Pr/LPS.