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. 2004 May;72(5):2753–2761. doi: 10.1128/IAI.72.5.2753-2761.2004

FIG. 4.

FIG. 4.

Ratios of specific to total IgA in lung lavage fluids of mice immunized i.n. with lactococci expressing TTFC (pTREX1-TTFC) or a control strain (pTREX1). Lung lavage fluids were collected from groups of six mice on days 7 (open bars), 20(striped bars), and 45 (shaded bars) post-initial treatment. The samples were tested by ELISA for TTFC-specific and total IgA. Bars, mean ratios; error bars, standard deviations. Asterisks indicate values significantly different from those for nonvaccinated controls (P < 0.05).