TABLE 2.
IL-4 and IFN-γ concentrations in culture supernatants of SPLC from mice immunized by i.p. injection of TT in FCA or the pTREX1 or pTREX1-TTFC lactococcal strain
| Stimulation | Cytokine concn (pg/ml) for mice immunized with:
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Nothing
|
TT-FCA
|
L. lactis (pTREX1-TTFC)
|
L. lactis (pTREX1)
|
|||||
| IL-4 | IFN-γ | IL-4 | IFN-γ | IL-4 | IFN-γ | IL-4 | IFN-γ | |
| None | 103.2 ± 6.6 | 292.0 ± 5.4 | 102.1 ± 4.0 | 607.5 ± 12.5 | 123.2 ± 5.5 | 275.0 ± 5.0 | 124.3 ± 5.0 | 275.0 ± 5.5 |
| LP-TT | 95.0 ± 5.8 | 365.0 ± 12.0 | 113.2 ± 5.1 | 637.0 ± 12.4 | 153.4 ± 6.1 | 354.0 ± 68.8 | 94.5 ± 4.6 | 279.5 ± 5.9 |
| pTREX1-TTFC | 148.7 ± 9.7 | 4,080 ± 118.6 | 193.4 ± 8.1 | 6,409 ± 182.2 | 161.6 ± 7.8 | 23,266 ± 456.3 | 98.1 ± 4.2 | 29,250 ± 558.0 |
| pTREX1 | 141.9 ± 6.3 | 4,080 ± 124.9 | 149.9 ± 6.5 | 6,352 ± 172.1 | 227.1 ± 10.3 | 20,306 ± 460.1 | 161.6 ± 7.8 | 40,502 ± 801.0 |