FIG. 5.

Restoration of anti-S. pyogenes resistance by reconstitution of carrageenan-treated mice with resident macrophages. Mice were treated with carrageenan, and one group was reconstituted with resident macrophages (solid bars) or injected with PBS (hatched bars) and then infected with S. pyogenes. Untreated mice were used as controls (CTR) (open bars). Bacteremia was determined after 24 and 48 h of bacterial inoculation. The bars represent the mean plus standard deviation of four mice per group. Statistical significance based on a comparison of carrageenan-treated and macrophage-reconstituted carrageenan-treated mice is indicated by an asterisk (P < 0.05). One representative experiment out of three is shown.