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. 2004 May;72(5):2956–2963. doi: 10.1128/IAI.72.5.2956-2963.2004

FIG. 7.

FIG. 7.

Effect of macrophage depletion either prior to infection or 12, 24, or 48 h after intravenous inoculation on resistance against S. pyogenes. Depletion of macrophages at each time point was performed by treatment with carrageenan or PBS for control (CTR) mice. (A) Survival times of macrophage-depleted and control mice monitored over a period of 10 days. Each group contained 10 mice. (B) Bacteremias of macrophage-depleted and control mice 48 h after bacterial challenge. CFU are expressed as mean values plus standard deviations of five mice per group (*, P < 0.05). One representative experiment out of five is shown.