Table IV.

Expression of other markers of interest in the tumor microenvironment^*

	mean.Control	Mean ChemoHormonal	mean AA	Standard Deviation.btw.pts	Standard Deviation Within patients	p.value: CH vs Ctrl	p.value: AA vs Ctrl
pAKT.epithelium.NUCL.	35.86	85.17	58.51	21.62	29.02	<0.001	0.002
pAKT.epithelium.CYTOPL.	85.33	80.90	70.71	17.39	20.03	0.417	0.009
pAKT.stroma.NUCL	8.15	14.70	5.67	8.05	8.85	0.011	0.327
pAKT.stroma.CYTOPL.	0.73	2.03	1.05	2.01	3.39	0.066	0.651
AKT.epithelium.NUCL.	85.12	95.81	94.21	9.00	16.46	0.001	0.006
AKT.epithelium.CYTOPL.	80.33	88.86	86.45	14.90	21.55	0.082	0.221
AKT.stroma.NUCL.	22.22	23.11	15.89	13.32	13.25	0.824	0.125
AKT.stroma.CYTOPL.	10.27	15.15	11.86	5.50	8.89	0.01	0.404
bcl2.epithelium.	3.72	13.46	7.78	14.73	12.70	0.027	0.358
bcl2 stroma.	5.10	7.25	9.24	4.95	6.67	0.174	0.011
p53 epithelium.	28.94	16.73	10.98	21.91	17.48	0.058	0.006
VEGF.epithelium.	66.25	86.52	71.37	21.52	23.74	0.003	0.439
VEGF.stroma.	16.15	36.12	36.35	17.63	13.51	<0.001	<0.001

^*Markers of interest included AKT, phosphor AKT, bcl2, p53 and VEGF