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Assessment of Ab responses and protection in mice immunized with recombinant BVH-3M or BVH-11M protein. (A) Flow cytometry analysis showing surface Ab binding to live heterologous strain WU2. Each square on the x axis represents units from 100 to 104, whereas the maximum cell number on each y axis is 64. (B and C) Protection elicited against heterologous challenges with strain WU2 in a sepsis model of infection (B) or with strain P4241 in a pneumonia model of infection (C).
