FIG. 2.

Infected mice given IL-12 displayed less inflammation and fewer granulomas. Hematoxylin and eosin staining was performed on 6-μm-thick formalin-fixed tissue sections at each time point postinfection. Magnification, ×2. At day 44 postinfection, WT and CD4^−/− mice treated with IL-12 (A and B) had less cellular infiltration and pathology than saline-treated mice (C and D). These sections are representative of CD4^−/− mice from three experiments and WT mice from four experiments.