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. 2013 Nov 26;6:84. doi: 10.1186/1757-2215-6-84

Figure 4.

Figure 4

Expression of SphK1 reversed the miR-124-induced inhibition of cellular migration and invasion. (A) The transfection of pcDNA3.1 (−)–SphK1 restored the expression of Sphk1 in SKOV3-ip cells even with miR-124 co-transfection. (B) Transwell assay and (C) Matrigel invasion assay of SKOV3-ip cells after co-transfection of NC or miR-124 mimics together with either pcDNA3.1 (−)-vector or pcDNA3.1 (−)-SphK1. ***denotes statistical significance at p < 0.001.