Table 2.

Multivariable analysis of risk factors associated with treatment failure at 14 days

Variable	OR	95% CI	P value
Community-associated strain type*	0·78	0·42–1·44	0·43
Never treated with an anti-MRSA antibiotic†	9·89	4·55–21·50	<0·0001
Charlson Comorbidity Index‡	1·11	1·01–1·23	0·03
APACHE II score‡	1·05	1·02–1·07	0·0003

OR, Odds ratio; CI, confidence interval.

^*Referent group is healthcare-associated strain type; community-associated strain type based on antibiotic susceptibility phenotype (minimum inhibitory concentration susceptible to gentamicin, clindamycin, and trimethoprim-sulfamethoxazole).

^†Referent group is those treated with an anti-MRSA antibiotic.

^‡These items measured each as continuous variables where odds ratio reflects changes for a one point change in the score.