Table 1. Statistical KS tests for the global tAI values that were calculated for 6 model organisms' proteomes.
| Organism | Groupsa | TMD non-SP | SP and TMD | Cytosolic |
| H. sapiens | SP non-TMD | 2.58e-11 | 1.08e-14 | 9.01e-12 |
| TMD non-SP | 0.0374 | 4.84e-4 | ||
| SP and TMD | 2.18e-5 | |||
| B. taurus | SP non-TMD | 3.96e-34 | 8.11e-9 | 9.18e-3 |
| TMD non-SP | 9.61e-4 | 7.42e-85 | ||
| SP and TMD | 2.22e-15 | |||
| D. melanogaster | SP non-TMD | 8.33e-10 | 5.36e-6 | 3.3e-4 |
| TMD non-SP | 0.488 | 7.19e-29 | ||
| SP and TMD | 8.82e-11 | |||
| C. elegans | SP non-TMD | 7.79e-22 | 5.01e-11 | 0.012 |
| TMD non-SP | 2.31e-4 | 2.84e-57 | ||
| SP and TMD | 1.22e-13 | |||
| S. cerevisiae | SP non-TMD | 6.48e-23 | 1.67e-12 | 3.3e-16 |
| TMD non-SP | 0.476 | 1.14e-11 | ||
| SP and TMD | 6.6e-3 | |||
| A. thaliana | SP non-TMD | 1.12e-17 | 1.24e-30 | 1.34e-6 |
| TMD non-SP | 3.28e-13 | 2.67e-10 | ||
| SP and TMD | 2.77e-28 |
aPartition of the proteomes to 4 exclusive groups is according to UniProtKB annotations for TMD and SP. Statistical significance <1.0e-5 is shown in bold.