Table 1. Demographic characteristics of the participants recruited in the study and specifications of blood collections and reference tests.
Origin | Recruitment period | Participant groups | Number of participants | Age range | Median age | Ratio male∶female | % with Chagas clinical signs | Volume of blood collected (mL) | ELISA | IIF | IHA |
Chile | 2004 and 2011 | Healthy endemic controls | 88 | Unknown | Unknown | Unknown | 0 | 3.0 | a | b | ND |
2009 | Chagas patients | 80 | 23–77 | 50.0 | 0.40 | 68 | 3.0 | a | b | ND | |
Argentina | 2008 to 2010 | Chagas patients | 73 | 18–77 | 50.0 | 0.78 | 43 | 5.0 | c | ND | d |
Spain | 2011 | Chagas patients | 34 | 15–51 | 43.0 | 0.48 | 56 | 2.5 | e | f | ND |
Notes: ND: not done; a: ELISA Chagas III, GrupoBios S.A., Chile; b: In house protocol with T. cruzi Tulahuen strain; c: Chagatest ELISA recombinant v. 4.0, Wiener Lab, Argentina; d: Chagatest HAI, Wiener Lab, Argentina; e: In house protocol with T. cruzi Dm28, MC & T strain; f: In house protocol with T. cruzi Dm28,MC & T strain.