Table 1. Basic characteristics of the included studies.
| Study | Year | Country | Ethnicity | Disease | Genotype | Sample size | % of male (case/control) | Age mean (case/control) | ||||||
| Case | Control | |||||||||||||
| C242T | TT | TC | CC | TT | TC | CC | ||||||||
| Inoue | 1998 | Japan | Asian | CAD | 2 | 26 | 173 | 0 | 53 | 148 | 201/201 | 0.70/0.70 | 59.8/54.9 | |
| Gardemann | 1999 | German | Caucasian | CAD | 207 | 748 | 751 | 65 | 208 | 226 | 1706/499 | 1.00/1.00 | 62.2/61.4 | |
| Li | 1999 | America | Other | CAD | 27 | 70 | 52 | 14 | 42 | 47 | 149/103 | 0.77/0.48 | 60/57 | |
| Cai | 1999 | Australia | Caucasian | CAD | 65 | 250 | 235 | 13 | 62 | 64 | 550/139 | 0.80/0.47 | 56.9/54.5 | |
| Saha | 1999 | India | Asian | CHD | 17 | 66 | 43 | 20 | 77 | 57 | 126/154 | 0.88/0.93 | 55.2/53.9 | |
| Saha | 1999 | China | Asian | CHD | 3 | 23 | 125 | 3 | 25 | 139 | 151/167 | 1.00/1.00 | 55.3/54.5 | |
| Lee | 2001 | Korean | Asian | CAD | 4 | 40 | 261 | 1 | 49 | 165 | 305/215 | 1.00/1.00 | 56.1/50.2 | |
| Stanger | 2001 | Australia | Caucasian | CAD | 15 | 50 | 43 | 6 | 24 | 15 | 108/45 | 1.00/1.00 | 52.9/54.2 | |
| Yamada | 2002 | Japan | Asian | MI | 25 | 319 | 1440 | 16 | 242 | 816 | 1784/1074 | 1.00/1.00 | 62.1/62.0 | |
| Zafari | 2002 | America | Other | CAD | 21 | 70 | 58 | 6 | 26 | 18 | 164/52 | 0.99/0.94 | 61.7/57.1 | |
| Balague | 2004 | Spain | Caucasian | AMI | 2 | 41 | 61 | 2 | 47 | 57 | 104/106 | 0.88/0/89 | 50.2/50.4 | |
| Murase | 2004 | Japan | Asian | MI/UA | 2 | 67 | 384 | 5 | 170 | 587 | 593/1595 | 0.76/0.48 | 50.0/60.6 | |
| Fan | 2006 | Finland | Caucasian | CAD | 12 | 66 | 172 | 10 | 56 | 86 | 250/152 | 0.77/0.58 | 62.0/55.0 | |
| Nasti | 2006 | Italy | Caucasian | CAD | 37 | 147 | 92 | 25 | 95 | 98 | 276/218 | 0.83/0.68 | 65.5/66.2 | |
| He MA | 2007 | China | Asian | CAD/MI | 2 | 32 | 531 | 2 | 64 | 543 | 565/609 | 0.57/0.52 | 61.9/64.7 | |
| Niemiec | 2007 | Poland | Caucasian | CAD | 25 | 80 | 67 | 18 | 85 | 66 | 172/169 | 0.67/0.70 | 43.8/34.2 | |
| Reyes | 2008 | Spain | Other | MI/UA | 48 | 137 | 119 | 47 | 145 | 123 | 304/315 | 0.78/0.74 | 56.0/54.5 | |
| Alexey | 2010 | Russia | Caucasian | CAD | 34 | 91 | 188 | 4 | 41 | 87 | 313/132 | 0.54/0.57 | 59.2/55.5 | |
| Goliasch | 2011 | Austria | Caucasian | AMI | 11 | 47 | 41 | 31 | 79 | 82 | 99/192 | 0.87/0.90 | 37.3/34.7 | |
| Najafi | 2012 | Italy | Caucasian | CAD | 23 | 47 | 44 | 12 | 32 | 24 | 114/68 | 0.68/0.32 | 62.8/55.9 | |
| A640G | GG | AG | AA | GG | AG | AA | ||||||||
| Inoue | 1998 | Japan | Asian | CAD | 82 | 83 | 36 | 80 | 79 | 42 | 201/201 | 0.70/0.70 | 59.8/54.9 | |
| Gardemann | 1999 | German | Caucasian | CAD | 313 | 735 | 438 | 141 | 251 | 107 | 1486/499 | 1.00/1.00 | 62.2/61.4 | |
| Zafari | 2002 | America | Other | CAD | 37 | 75 | 37 | 13 | 25 | 12 | 149/50 | 0.99/0.94 | 61.7/57.1 | |
| Reyes | 2008 | Spain | Other | MI/UA | 104 | 155 | 46 | 48 | 165 | 96 | 305/309 | 0.78/0.74 | 56.0/54.5 | |
| Goliasch | 2011 | Austria | Caucasian | AMI | 23 | 47 | 28 | 39 | 103 | 50 | 98/192 | 0.87/0.90 | 37.3/34.7 | |
| Niemiec | 2011 | Poland | Caucasian | CAD | 39 | 68 | 53 | 40 | 75 | 45 | 160/160 | 0.68/0.76 | 43.8/59.3 | |
Abbreviations: N, Number of studies OR, Odds ratio; 95% CI, 95% confidence interval; REM, random-effects model; FEM, fix-effects model.