Table 2. Initial pooled estimates and stratified analysis for the association between polymorphisms and CAD.
| Genetic Model | N | Model for analysis | OR (95% CI) | P for heterogeneity | I 2 (%) | P for Egger’s test |
| C242T | ||||||
| Allelic model | 20 | REM | 0.93(0.82,1.05) | <0.0001 | 67.88 | 0.6768 |
| Asian | 7 | FEM | 0.75(0.67,0.84) | 0.0618 | 52.16 | 0.6371 |
| Caucasian | 10 | FEM | 1.04(0.95,1.14) | 0.0599 | 48.31 | 0.7246 |
| Other | 3 | FEM | 1.09(0.91,1.30) | 0.3400 | 10.75 | 0.7679 |
| Dominant model | 20 | REM | 0.89(0.76,1.04) | <0.0001 | 68.15 | 0.9351 |
| Asian | 7 | FEM | 0.69(0.61,0.79) | 0.0522 | 52.30 | 0.7497 |
| Caucasian | 10 | FEM | 1.04(0.93,1.18) | 0.0685 | 47.86 | 0.4538 |
| Other | 3 | FEM | 1.09(0.85,1.40) | 0.2730 | 21.63 | 0.8526 |
| Recessive model | 19 | FEM | 1.07(0.92,1.25) | 0.8181 | 0.00 | 0.2440 |
| A640G | ||||||
| Allele contrast | 6 | REM | 1.06(0.79,1.43) | <0.0001 | 86.73 | 0.5087 |
| Dominant model | 6 | REM | 1.04(0.69,1.58) | <0.0001 | 80.75 | 0.4531 |
| Recessive model | 6 | REM | 1.14(0.74,1.76) | <0.0001 | 83.45 | 0.4144 |
Abbreviations: N, Number of studies OR, Odds ratio; 95% CI, 95% confidence interval; REM, random-effects model; FEM, fix-effects model.