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. 2014 Jan 2;9(1):e84471. doi: 10.1371/journal.pone.0084471

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Panel A. Total ion current for a typical sample from an individual with BOS. Panel B. Total ion current for a control subject who did not develop BOS within at least 100 months. The intensity has been adjusted to the same maximum as Panel A. The large peak at 1.48 minutes corresponded to lidocaine. Panel C. Extracted ion current for the +4 charge state of a component at m/z = 410.98. Only peak b represented a monoisotopic ion. Peaks a and c were isotopes of other compounds.