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. 2014 Jan 2;9(1):e84583. doi: 10.1371/journal.pone.0084583

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Metabolite concentrations were determined by triple-quadrupole mass spectrometry and normalized to millimoles of creatinine for urine samples (A–D) and to milligrams of tissue weight for liver samples (E). P-values for differences in metabolite concentrations between genotypes are indicated (* = statistically significant, p<0.05). PAG: Phenylacetylglycine. WT: Hmgn5^+/y; N5KO: Hmgn5^tm1/Y. Analyses were done with 7 N5KO and 5 WT mice.