Table 1. Blood chemistry values affected by the loss of HMGN5.
Measure | Hmgn5+/+ (mean ± SD) | Hmgn5tm1/y (mean ± SD) | P-value |
Overnight Fasted Mice | |||
Fasting triglycerides (mmol/L) | 1.24±0.3 | 1.58±0.4 | 0.05 |
Fasting non-HDL cholesterol (mmol/L) | 0.57±0.1 | 0.66±0.1 | 0.027 |
Fed Mice | |||
Albumin (g/L) | 25.4±0.8 | 26.4±1.1 | 0.032 |
Pancreatic α-amylase activity (U/L) | 664±67 | 583±55 | 0.01 |
Calcium (mmol/L) | 2.35±0.0 | 2.43±0.1 | 0.01 |
Table list altered parameters that differed significantly between Hmgn5+/+ and Hmgn5tm1/Y littermate mice. 10 male mice of each genotype were analyzed.