Table 2. Signaling pathways involving proteins upregulated after sublethal proton beam irradiation.

Pathway	Regulated proteins (reference)
MAPK	MVP (Valenciano et al., 2012) [63]
AKT/PI3	MVP (Blanco-Aparicio et al., 2007) [103]
	PDCD6 (Rho et al., 2012) [69]
	VCP (Braun and Zischka, 2008) [74]
	Lamin A/C (Kong et al., 2012) [41]
PTEN	MVP (Lara et al., 2011) [104]
	MCM-7 (Luo et al., 2011) [58], (Poliseno et al., 2010) [59]
	Lamin A/C (Kong et al., 2012) [41]
p-53	MVP (Lloret et al., 2009) [105]
	STRAP (Seong et al., 2007) [106]
	PDCD6 (Suzuki et al., 2012) [68]
	Caprin-1 (Saffari et al., 2009) [66]
Cell cycle	MCM-7, G1/S phase (Mukherjee et al., 2009) [56]
	Caprin-1, G1/S phase (Wang et al., 2005) [65]
	Caprin-1, cyclin D2 (Solomon S. et al., 2007) [46]
TGF-β	STRAP (Seong et al., 2007) [106]
nFκB	VCP (Braun and Zischka, 2008) [74]
	PDCD6 (Park et al., 2012) [70]