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. 2014 Jan 2;9(1):e84877. doi: 10.1371/journal.pone.0084877

Figure 1. Consumption of probiotic microbes increases the weight of mouse testes.

Figure 1

a. Gross appearance of outbred Swiss male mice with oral Lactobacillus reuteri treatment at 12 months of age. Testes of L. reuteri-fed mice are larger compared to control mice. b–e. Results of statistical analyses of testes weight at different time-points after starting treatment, including the (b) 5, (c) 7, (d) 9 and (e) 12 months of age time-points. L. reuteri consistently increased testicular weight in both control- and new western-diet-fed mice compared to age- and diet-matched controls. Dietary supplementation with L. reuteri, but not with E coli K12, increased testicular weight in control-diet-fed mice at age 7 months when compared to age- and diet-matched controls (c). Numbers on the y-axis of bar graphs correspond to the mean±SEM of testes weight or the testicular weight; *p<0.05, **p<0.001.