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. 2014 Jan 2;10(1):e1003858. doi: 10.1371/journal.ppat.1003858

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© 2014 Rangaswamy, Speck

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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IRF4^fl/fl mice were infected with 1000 PFU of either MHV68-Cre or MHV68-WT virus intranasally. On day 16 post infection, splenocytes were analyzed by limiting dilution analyses to determine (A) the frequency of virus capable of establishing latency and (B) the frequency of virus capable of reactivating from latency.