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. 2013 Nov 14;289(1):215–228. doi: 10.1074/jbc.M113.525550

FIGURE 5.

FIGURE 5.

Phagocytosis of LOS mutants by murine macrophages. A, schematic representation of the different subspecies of LOSs and the intermediates identified in this study. NAc-Gal, N-acylated dideoxygalactose. R1, R2, and R3 represent the acyl chains. B, phagocytosis rate of the various LOS mutants by J774 macrophages normalized to 1 for the wild-type strain. Results are expressed as means ± S.E. (error bars) from three to five independent experiments. C, phagocytosis rates of the wbbL2, MMAR_2331, and MMAR_2321 mutants and complemented (_C) strains. D, kinetics of phagocytosis of the wbbL2 mutant. For C and D, results are representative of two independent experiments and are expressed as means ± S.D. (error bars) of triplicates. E, percentages of mycobacteria-containing macrophages determined by counting infected cells under the microscope. Results are expressed as means ± S.E. (error bars) from three independent experiments.