FIGURE 5.

The effect of cocaine and methylphenidate on synapsin I activation in striatal presynaptic terminals. A–C, representative immunoblots of synapsin I (syn I) and synapsin phosphorylation (p-syn) are shown in different experimental conditions. Sulpiride (5 μm) was always present throughout the experiment. Ctrl, control; Coca, cocaine. B–D, quantification of phosphorylation of synapsin was expressed as ratio of anti-phospho-synapsin on anti-synapsin I. Values are mean ± S.E. of five experiments. *, p < 0.05 versus control.