FIGURE 1.

Latrophilin-1 and -3 (Lphn1 and Lphn3) are primarily expressed in brain in a developmentally regulated manner, whereas latrophilin-2 (Lphn2) is ubiquitously expressed. A, quantitative RT-PCR measurements of the latrophilin-1, -2, and -3 (Lphn1, Lphn2, and Lphn3) mRNAs in the brain, liver, heart, and kidney of adult mice. mRNA levels were normalized to those of GAPDH monitored in the same samples. B, quantitative RT-PCR measurements of the Lphn1, Lphn2, and Lphn3 mRNAs in brain at postnatal days 1 (p1), 8 (p8), 15 (p15), 22 (p22), and in adult brain. All mRNA levels were normalized to those of actin as an internal control and then to the mRNA levels of the respective latrophilin at p1. Data shown are means ± S.E. (n = 4).