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. 2013 Nov 12;289(1):476–484. doi: 10.1074/jbc.M113.504472

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FIGURE 6. — Dose-response curves of NOsGC wild-type enzyme and NOsGC mutants. Concentration-dependent activation of α₁S/β₁, α₁S-W352F,W669A/β₁-W22F,W602F and α₁S-W466F/β₁ was measured in a range of 1 nm to 100 μm DEA/NO or 0.1 nm to 100 μm BAY 41-8543 in the presence of DEA/NO (100 μm). A, fold stimulation by DEA/NO. B, fold stimulation by BAY 41-8543 in the presence of DEA/NO. C and D, same data as in A and B normalized to the maximum. The results are expressed as means ± S.E. of at least three independent experiments.