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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Lab Invest. 2013 Nov 11;94(1):10.1038/labinvest.2013.133. doi: 10.1038/labinvest.2013.133

Figure 5. Glucagon-like peptide-1 receptor (GLP-1R) expression in activated pancreatic stellate cells (α-SMA positive) and surrounding areas in the pancreas of Wistar/Bonn Kobori (WBN/Kob) rats (a chronic pancreatitis rat model).

Figure 5

Expression of GLP-1R and alpha-smooth muscle actin (α-SMA: markers for activated PSCs) in the pancreas of 15-week-old WBN/Kob chronic pancreatitis model rats was examined by immunofluorescence staining. Panels A–D are 500x magnification and the area in the square is shown in the insert at 1000x. Shown are GLP-1R expression (in green: A), α-SMA (in red: B) and nuclei (in blue: C). A merged image is shown in Panel D. This figure shows in a chronic pancreatitis model, the marked GLP-1R expression co-localizes with activated PSCs (α-SMA positive). These pictures are representative images from four experiments. DC: ductal cells.