. 2013 Sep 25;13(1):18–29. doi: 10.1074/mcp.M113.030569

Table I. List of proteins coded by mRNA predicted as targets of miR-378 and/or miR-378^*.

miR	Spot number^a	Accession^b	Protein name^b	mirSVR^c	miRanda^c	Context+^c	Cons^d	Function^e
Target of miR-378	8, 11, 12	ACTN4_RAT	Alpha-actinin-4	−0.5918			M, H	Actin crosslink formation
	17, 18, 19	GELS_RAT	Gelsolin		16.0005		M	Actin filament capping
	27, 36	DPYL3_RAT	Dihydropyrimidinase-related protein 3			−0.04		Actin crosslink formation
	54	GMPPA_RAT	Mannose-1-phosphate guanyltransferase a	−0.0115			M, H	GDP-mannose biosynthetic process
	70	DDAH1_RAT	Dimethylarginine dimethylaminohydrolase 1			0.09	M, H	Arginine metabolic process
	91, 92	LDHA_RAT	l-lactate dehydrogenase A chain	−0.0181			M	Glycolysis, lactate metabolic process
	95	CNN3_RAT	Calponin-3	−0.1071			M	Actomyosin structure organization
	115	1433G_RAT	14-3-3 protein gamma	−0.0009				Signal transduction
	117	1433T_RAT	14-3-3 protein theta	−0.0649			M	Protein binding
	119	CYBP_RAT	Calcyclin-binding protein			−0.27		Cardiac muscle cell differentiation
	122	1433Z_RAT	14-3-3 protein zeta/delta	−0.0182				Protein targeting to mitochondrion
Target of miR-378^*	33, 34	VIME_RAT	Vimentin	−0.0401			M, H	Intermediate filament organization
	45, 47, 49, 51, 53	CALU_RAT	Calumenin	−0.0270			M, H	Response to organic cyclic compound
	59	ACTS_RAT	Actin, alpha skeletal muscle	−0.0106			M, H	Heart contraction
	74, 79	TPM2_RAT	Tropomyosin beta chain		16.3864			Regulation of ATPase activity
	89, 96, 98, 100	TPM1_RAT	Tropomyosin alpha-1 chain	−0.0083				Sarcomere organization
	125	PARK7_RAT	Protein DJ-1	−0.2971				Negative regulation of cell death
Targets of both miRs	25.26	GRP78_RAT	78 kDa glucose-regulated protein	−0.2755^*	18.8279^*	−0.16	M, H	ER response, response to glucose starvation
	37, 38	TBB5_RAT	Tubulin beta-5 chain	−0.0908/−0.0041^*				Microtubule-based movement
	142	PPIA_RAT	Peptidyl-prolyl cis trans isomerase A	−0.4677^*	17.3748		M, H	Protein folding

^a Spot number refers to Fig. 1.

^b Uniprot accession ID and protein name.

^c MiR target scores. Microrna.org: mirSVR, microcosm: miRanda, Targetscan: context + *, score for miR-378* when mRNA is predicted as a target for both miRs.

^d Conservation of the rat binding site with mouse (M) and human (H).

^e Biological function indicated by GO database.

Table I. List of proteins coded by mRNA predicted as targets of miR-378 and/or miR-378*.

Table I. List of proteins coded by mRNA predicted as targets of miR-378 and/or miR-378^*.