Fig. 3.

Score plot and loadings of principal component analysis from quantified proteins in LIS fraction of vastus lateralis from mature and old women. Discriminations are on principal component 1, and revealed the protein expressions related to muscle aging. The pink line delineates the mature women (pink circles) and the blue line delineates the old women (blue circles). The differentially expressed proteins are marked by abbreviations: ACADM, medium-chain specific acyl-CoA dehydrogenase, mitochondrial; ACTB, actin, cytoplasmic 1; AHSG, alpha-2-HS glycoprotein; ANKRD2, ankyrin repeat domain-containing protein 2; ANXA2, annexin 2; APEH, acylamino-acid-releasing enzyme; ATP5A1, ATP synthase subunit alpha, mitochondrial; ATP5B, ATP synthase subunit beta, mitochondrial; BLVRB, flavin reductase (NADPH); C4A, complement C4-A; CA3, carbonic anhydrase 3; CFL1, cofilin-1; CRAT, carnitine O-acetyltransferase; EEF2, elongation factor 2; FABP4, fatty acid-binding protein, adipocyte; FGA, fibrinogen alpha chain; FH, fumarate hydratase, mitochondrial; FLNC, filamin-C; GOT2, aspartate aminotransferase, mitochondrial; HBG1, hemoglobin subunit gamma-1; HSPA4, heat shock 70 kDa protein 4; HV304, Ig heavy chain V-III region TEI; KV402, Ig kappa chain V-IV region Len; LDHB, l-lactate dehydrogenase B chain; MYH1, myosin-1; MYL1, myosin light chain 1/3, skeletal muscle isoform; OAS2, 2′-5′-oligoadenylate synthase 2; PFKL, 6-phosphofructokinase, liver type; PRKAR2A, cAMP-dependent protein kinase type II-alpha regulatory subunit; RPS27A, ubiquitin-40S ribosomal protein 27A; SLC25A4, ADP/ATP translocase 1; TAGLN, transgelin; TALDO1, transaldolase; TTN, titin; YWHAE, 14–3-3 protein epsilon.