Table 3.
Prevalence and Odds of ADHD symptoms in Children After Exposure to Increasing Maternal Serum Thyroid Stimulating Hormone Concentration in Early Pregnancy
| All Mother-Children Pairs With Sufficient Maternal Serum Samples and Children's ADHD Symptom Evaluation Available (n = 5131) | ||
|---|---|---|
| Child's ADHD symptom | n (%) | aOR (95% CI)a |
| Inattention | ||
| Boys | 749 (14.6) | 1.00 (0.90–1.12) |
| Girls | 281 (5.5) | 1.18 (1.02–1.37) |
| Hyperactivity | ||
| Boys | 806 (15.7) | 1.00 (0.90–1.10) |
| Girls | 289 (5.6) | 1.10 (0.95–1.25) |
| Rutter B2 scores of 9 or greater | ||
| Boys | 494 (9.6) | 1.02 (0.90–1.15) |
| Girls | 192 (3.7) | 1.23 (1.03–1.48) |
| Combined ADHD | ||
| Boys | 355 (6.9) | 1.17 (1.00–1.36) |
| Girls | 106 (2.1) | 1.39 (1.07–1.80) |
Abbreviations: aOR, adjusted odds ratio.
a
The ORs with 95% CIs for ADHD symptoms in the child per 1 natural logarithmic unit increase in maternal early-pregnancy TSH concentrations are calculated with logistic regression after adjusting for having more than two children in family, maternal smoking, maternal education, and maternal age.