Table 2.
Laboratory and Imaging Results of Study Samplea
| Variable | Men (n = 197) | Women (n = 253) | All (n = 450) | P Value |
|---|---|---|---|---|
| Sclerostin, pg/mL | 1217 ± 447 (1119) | 1043 ± 343 (988) | 1119 ± 401 (1040) | <.0001 |
| Aortoiliac CP mass, mg Ca2+ | 1834 ± 3370 (328) | 1442 ± 2494 (224) | 1613 ± 2910 (282) | .0717 |
| Aortoiliac CP mass > 0, % | 81.3 | 73.3 | 76.8 | .0466 |
| Carotid CP mass, mg Ca2+ | 61.6 ± 165.5 (1.0) | 34.2 ± 98.0 (0.0) | 46.2 ± 132.4 (0.0) | .0211 |
| Carotid CP mass > 0, % | 51.8 | 43.4 | 47.1 | .079 |
| Coronary CP mass, mg Ca2+ | 373.4 ± 678.8 (45.0) | 215.4 ± 616.0 (4.0) | 284.3 ± 648.2 (13.0) | .0005 |
| Coronary CP mass > 0, % | 68.2 | 58.7 | 62.9 | .0398 |
| Serum creatinine, mg/dL | 1.1 ± 0.3 (1.0) | 0.9 ± 0.3 (0.8) | 1.0 ± 0.3 (0.9) | <.0001 |
| C-reactive protein, mg/dL | 0.7 ± 1.1 (0.3) | 1.4 ± 2.3 (0.7) | 1.1 ± 1.9 (0.5) | <.0001 |
| MCP-1, pg/mL | 248.6 ± 107.4 (227.6) | 236.6 ± 101.0 (212.7) | 243.3 ± 104.7 (218.7) | .1867 |
| Urine ACR, mg/g | 144.7 ± 490.1 (24.1) | 148.3 ± 598.9 (11.1) | 146.7 ± 552.9 (15.0) | .0166 |
| GFR,(ml/min/1.73 m2 | 97.0 ± 26.6 (92.6) | 93.8 ± 27.7 (93.7) | 95.2 ± 27.3 (93.3) | .217 |
| Fasting glucose, mg/dL | 158.1 ± 68.6 (140.0) | 144.4 ± 61.5 (130.0) | 150.4 ± 65.0 (134.5) | .0299 |
| HbA1c, % | 8.2 ± 1.9 (7.9) | 8.0 ± 2.0 (7.6) | 8.1 ± 2.0 (7.7) | .2643 |
| Total cholesterol, mg/dL | 173.9 ± 47.5 (169.0) | 184.1 ± 44.6 (176.0) | 179.7 ± 46.1 (173.0) | .007 |
| HDL-cholesterol, mg/dL | 44.5 ± 12.1 (43.0) | 50.5 ± 14.3 (48.0) | 47.8 ± 13.7 (46.0) | <.0001 |
| LDL-cholesterol, mg/dL | 102.4 ± 35.7 (98) | 109.3 ± 37.8 (100) | 106.3 ± 37 (100) | .576 |
| Triglycerides, mg/dL | 139.4 ± 178.6 (105.0) | 123.4 ± 104.2 (97.0) | 130.4 ± 141.7 (101.0) | .336 |
| TvBMD, mg/cm3 | 202.2 ± 48.7 (199.7) | 209.5 ± 55.0 (205.3) | 206.3 ± 52.4 (204.8) | .203 |
| LvBMD, mg/cm3 | 179.4 ± 44.5 (179.5) | 181.7 ± 48.9 (177.8) | 180.7 ± 47.0 (179.0) | .6464 |
Abbreviations: HDL, high-density lipoprotein; LDL, low-density lipoprotein; MCP-1, monocyte chemotactic protein-1.
a
Unless indicated otherwise, results are shown as mean ± SD (median). P values are derived from the test comparing the distributions between men and women.