Table 1.
Subject Characteristics Before Randomizationa
| Before Placebo (n = 12) | Before E2 (n = 12) | |
|---|---|---|
| Age, y | 62 ± 1.5 | 68 ± 2.6 |
| BMI, kg/m2 | 27 ± 1.2 | 27 ± 1.3 |
| T, ng/dL | 19 ± 3.4 | 20 ± 4.3 |
| E2 , pg/mL | 9.9 ± 0.8 | 10 ± 0.4 |
| E21, pg/mL | 28 ± 4.3 | 29 ± 4.1 |
| LH, IU/L | 32 ± 6.0 | 26 ± 3.6 |
| FSH, IU/L | 84 ± 13 | 71 ± 7.4 |
| SHBG, nM | 56 ± 4.0 | 60 ± 6.2 |
| IGF-1, μg/L | 143 ± 30 | 102 ± 7.1 |
| IGFBP-1, μg/L | 35 ± 7.7 | 42 ± 7.9 |
| IGFBP-3, mg/L | 4.0 ± 0.3 | 4.1 ± 0.2 |
a
Unpaired t tests yielded estimated P > .05 for all comparisons, except age (P = .037). Multiply T, E2, and E1 by 0.0347, 3.67, and 3.70, respectively, for SI units.