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. Author manuscript; available in PMC: 2014 Jan 3.
Published in final edited form as: Kidney Int. 2011 Mar 9;80(2):10.1038/ki.2011.56. doi: 10.1038/ki.2011.56

Figure 4. No aberrant β-catenin activity is observed in Pkd2/WS25 mice.

Figure 4

Paraffin-embedded kidney sections from 2 week old Pkd2/WS25 embryos carrying the TCF/β-catenin-lacZ reporter showed normal restriction of canonical WNT activity and a few cysts (top panel). At 8 weeks of age, cysts are clearly visible in the Pkd2/WS25 kidneys but no β-catenin activity was observed (bottom panel). Scale bars represent 20µm.