FIGURE 5.

(A,B) Effects of a unilateral vestibular neurectomy on the density of [³H]N-α-methylhistamine binding sites in the three parts of the inferior olive. Changes in histamine H₃ receptor binding in the inferior olive 1 (A) or 3 (B) weeks after unilateral vestibular neurectomy. Results are expressed as mean values and standard errors of femtomole of [³H]N-α-methylhistamine specifically bound per milligram of protein from autoradiograms. Data from the medial (MIO), the dorsal (DIO), and the posterior (PIO) parts of inferior olive are given as the average value of the right and left structures for the controls (black histograms); they are provided separately for each side [lesioned (thick hatched histograms) versus intact (thin hatched histograms)] for the cats killed 1 (A) or 3 (B) weeks after unilateral vestibular neurectomy. **P < 0.0001.