FIGURE 6.

(A,B) Effects of a unilateral vestibular neurectomy on the density of [³H]N-α-methylhistamine binding sites in the different subregions of the PIO. Changes in histamine H₃ receptor binding in the different subregions of the PIO 1 (A) or 3 (B) weeks after unilateral vestibular neurectomy. Results are expressed as mean values and standard errors of femtomole of [³H]N-α-methylhistamine specifically bound per milligram of protein from autoradiograms. Data from the dorsomedial cell column (DMCC), the dorsal cap (DC), the beta nucleus (b nucleus) and the ventrolateral outgrowth (VLO) are given as the average value of the right and left structures for the controls (black histograms); they are provided separately for each side [lesioned (thick hatched histograms) versus intact (thin hatched histograms)] for the cats killed 1 (A) or 3 (B) weeks after unilateral vestibular neurectomy. **P < 0.0001.