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Ectopic expression of DeltaC and Notch-NICD alter stripes. (A-C) Expression of DeltaC (B) and the Notch1a intracellular domain (C) in melanophores resulted in fewer, wider stripes than those in wild type (A). (D) Width of black stripes in transgenic fish [wild type, n=12; Tg(mitfa:deltaC), n=12; Tg(mitfa:NICD1a), n=13]. *P<0.0001 (Student’s t-test). Error bars represent s.d. Scale bar: 1 mm.
