Table 3.

Integrin-associated intracellular proteins in Drosophila.

Integrin-associated intracellular proteins in Drosophila. “Class” indicates whether the proteins: always co-localize with their receptor and are required for all functions (1 – core components), for some functions (2A-B) or for no described function (2C) of the receptor; co-localize with their receptor in certain contexts and are required for some functions of the receptor (3A). See text and figure 1 for more details.

^*indicates that the class is predicted. “L” (co-Localization) indicates whether the proteins localize with their receptors in all (full black) or some tissues (half black). “I” (Interaction) indicates whether the Drosophila proteins have been shown to (+) or are predicted to (P) interact biochemically with their receptor. “Ph” (Phenotype) indicates whether the protein is required for more functions (full black), some functions () or for no described function () of its receptor. “Tissue” describes in which tissue the protein localizes (L) and shares phenotypes (Ph) with its receptor. “Function” describes the relevant processes described requiring the protein for its receptor function. “RNAi” indicates functions observed when the gene is down-regulated by RNAi in some tissues. References: Alatortsev (1997) FEBS Lett. 413 197-201; Bai (2008) Development 135 1439-1449; Bataille (2010) Dev. Cell 19 317-328; Brown (2002) Dev. Cell 3 569-579; Clark (2003) Development 130 2611-2621; Grabbe (2004) Development 131 5795-5805; Huang (2007) Development 134 2337-2347; Jani (2007) J. Cell Biol. 179 1583-1597; Kadrmas (2004) J. Cell Biol. 167 1019-1024; Loer (2008) Nat. Cell Biol. 10 422-428; Murakami (2007) Development 134 1539-1548; Torgler (2004) Dev. Cell. 6 357-369; Vakaloglou (2012) J. Cell Sci. ahead of print; Zervas (2001) J. Cell Biol. 152 1007-1018