Table 3.

Haplotype frequency distribution between patients and controls

Haplotype	Patients	Controls	Comparisons of groups	OR (95 % CI)	p-value
A – T	0.193	0.466	A vs. T	1.00	–
G – C	0.031	0.223	G vs. C	1.48(0.47–4.66)	0.5
G – T	0.485	0.289	G vs. T	0.83(0.28–2.49)	0.74
A – C	0.291	0.023	A vs. C	0.42(0.05–3.64)	0.43
Combination	Patients	Controls	Comparisons of groups	OR (95 % CI)	p-value
	N (%)	N (%)
1	7(2.5)	4(1.3)	1 vs. 2 + 3	1.91(0.55–6.61)	0.37
2	105(37.1)	164(53.6)	2 vs. 1 + 3	0.51(0.36–0.71)	<0.001*
3	171(60.42)	138(45.1)	3 vs. 1 + 2	1.86(1.33–2.57)	<0.001*
χ 2 = 15.23; p = 0.00049*

1 - G-G/T-T; 2- G-G/T-C, G-G/C-C, G-A/T-T, A-A/T-T; 3 - G-A/T-C, G-A/C-C, A-A/T-C, A-A/C-C

OR odds ratio, CI Class Interval

*Significant at 5 % level of significance