Table 3.

Differences in risk factors and prescribing between bipolar and controls for coronary heart disease (CHD) and hypertension patients standardised by age and gender

Patients	Bipolar	Controls	Odds ratio (95% CI)
CHD patients:	n = 170	n = 80,985
Current smokers, %	32.3	20.6	1.55 (1.11 to 2.17) P = 0.01
Ever smokers, %	67.6	63.3	1.00 (0.73 to 1.37) P = 0.95
	n = 147	n = 73,508
Total cholesterol >5, %	18.6	18.3	1.02 (0.73 to 1.37) P = 0.95
	n = 170	n = 80,863
Blood pressure not controlled, %*	1.1	2.3	0.24 (0.03 to 1.74) P = 0.16
Prescribed drugs	n = 170	n = 81,297
Aspirin or clopidogrel, %	69.3	73.6	0.81 (0.58 to 1.12) P = 0.20
Statin, %	70.0	74.9	0.69 (0.50 to 0.96) P = 0.02
No antihypertensive, %	29.4	15.8	2.08 (1.49 to 2.91) P <0.001
One antihypertensive, %	37.6	31.3	1.29 (0.94 to 1.76) P = 0.10
Two or more antihypertensives, %	32.9	52.7	0.46 (0.33 to 0.63) P <0.001
Hypertension patients:	n = 462	n = 232,986
Current smokers, %	27.9	17.1	1.87 (1.53 to 2.39) P <0.001
Ever smokers, %	54.5	48.9	1.25 (1.04 to 1.50) P <0.001
	n = 462	n = 232.915
Blood pressure not controlled, %*	6.5	6.6	0.94 (0.64 to 1.37) P = 0.77
Prescribed drugs	n = 462	n = 233,852
Statin, %	36.7	41.5	0.82 (0.68 to 0.98) P = 0.04
No antihypertensive, %	21.8	13.9	1.70 (1.36 to 2.12) P <0.001
One antihypertensive, %	39.8	32.3	1.38 (1.15 to 1.67) P <0.001
Two or more antihypertensives, %	37.8	53.7	0.53 (0.44 to 0.68) P <0.001

Prescribing based on previous 84 days. Antihypertensives include any angiotensin-converting enzyme inhibitor (ACEI), angiotension II receptor blocker (ARB), beta blocker, calcium channel blocker, thiazide, alpha blocker, spironolactone or other antihypertensive.

*Blood pressure not controlled calculated as systolic blood pressure (SBP) ≥140 plus diastolic blood pressure (DBP) ≥90 if aged under 80, and SBP ≥150 plus DBP ≥90 if aged 80 and over.