Table 2.

Cohort 1: gray matter (GM) regions discriminating between individuals with bipolar disorder (BD) and controls

Region	Laterality	BA	Coordinates			Cluster sizea	Wi b
			x	y	z
Frontal lobe
Middle frontal gyrus	R	10	33.3	49.9	11.7	466	−16.7
	L	10	−31.6	55.3	7.7	397	−16.6
		9	−39	23.9	27.7	93	−21.8
Inferior frontal gyrus	L	11	−30.6	35.8	−16.9	71	−14.0
Parietal lobe
Inferior parietal lobule	R	40	39.6	−54	41	221	−22.4
	L	40	−43.1	−35.8	44.5	569	−16.8
Temporal lobe
Superior temporal gyrus	R	41	48.1	−32.1	15.2	76	−14.5
	L	39	−52.8	−55.4	23.5	832	−18.4
Fusiform gyrus	L	37	−45.7	−59.7	−14.7	210	−16.1
Middle temporal gyrus	R	21	57.3	−37.8	−2.4	155	−13.6
	L	37	−56.6	−54.1	−8.9	204	−16.3
Occipital lobe
Lingual gyrus	R	19	33.3	−63.1	2.7	1759	−18.2
		17	7.2	−94.1	2.9	111	−18.0
Cuneus	L	18	−4.3	−76.4	6.3	109	−10.0
Superior occipital gyrus	L	19	−31.6	−72.9	26.4	84	−15.6
Middle occipital gyrus	R	19	29	−76.3	24.2	53	−18.0
Limbic lobe
Parahippocampal gyrus	R	28	20.8	−14.6	−19.6	55	−12.8
Anterior cingulate gyrus	L	32	−0.4	48.8	5.55	179	−11.7
Posterior cingulate gyrus	R	31	0.4	−37.9	40.4	759	−12.2
		30	−9.5	−60.4	12.2	71	−9.2
Insula	R	13	34.7	9.6	2.2	707	−14.1
	L	13	−38.7	16.2	−1.4	747	−15.5
Thalamus	L	–	0	−18.1	6	184	−14.6
Striatum
Caudate	R	–	11	15.7	5.7	50	−12.2
	L	–	7	16.9	6.7	77	–16.1
Cerebellum	L	–	20.8	−61.4	−53.4	582	−16.2
	R	–	−28.9	−66.3	−52.6	257	−12.5

BA, Brodmann area; R, right; L, left.

Coordinates are shown in Montreal Neurological Institute (MNI) standard space; x = sagittal, y = coronal, z = axial.

^aNumber of voxels.

^bHighest weights within individual clusters.