Table 1.
Visit 1 |
Visit 2 |
Visit 3 |
|
---|---|---|---|
25 months |
26 months |
28 months |
|
Raw (Z-score) | Raw (Z-score) | Raw (Z-score) | |
Global cognition |
|
|
|
MMSE |
261 |
242 |
16 |
Memory |
|
|
|
CVLT trial 5 |
4 (−4.00) |
4 (−4.00) |
0 (−5.00) |
CVLT delay |
1 (−4.00) |
1 (−4.00) |
0 (−4.00) |
CVLT recog hits |
15 (0.00) |
15 (0.00) |
13 (−1.00) |
CVLT recog false pos |
3 (−0.50) |
3 (−0.50) |
16 (−4.00) |
Benson figure delay recall |
3 (−4.17) |
0 (−5.48) |
N/D |
Mean memory Z-score |
−2.53 |
−2.80 |
−3.50 |
Executive function |
|
|
|
Modified trails |
59" (−3.00) |
119" (−8.62) |
120" (−8.71) |
Design fluency |
N/A |
5 (−2.28) |
0 (−4.07) |
Digit backwards span |
3 (−1.85) |
3 (−1.85) |
3 (−1.85) |
Stroop inhibition |
31 (−2.25) |
19 (−3.50) |
N/D |
Mean executive Z-score |
−2.37 |
−4.06 |
−4.88 |
Language |
|
|
|
BNT-Abbrev |
13 (−1.66) |
15 (+0.55) |
N/D |
Visuospatial |
|
|
|
Benson figure copy | 13 (−1.27) | 14 (−1.36) | N/D |
1 Missed 2 points for orientation and 2 on recall. 2 Missed 3 points for orientation and 3 on recall. Abbreviations and Definitions:MMSE Mini-Mental State Examination, CVLT California Verbal Learning Test-II (16 word list), Recog Recognition, False Pos False Positive Total, Modified Trails Abbreviated trail-making task using numbers and days of the week, BNT-Abbrev Abbreviated (15-item) Boston Naming Test, N/D patient unable to perform, N/A not administered.