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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Invest New Drugs. 2013 Oct 10;31(6):10.1007/s10637-013-0034-9. doi: 10.1007/s10637-013-0034-9

Figure 1.

Figure 1

SN38 AUC (ng/ml*hr) according to UGT1A1 *28 genotype. Pharmacokinetic data were obtained for UGT1A1 *1/*1 and *1/*28 patients treated with irinotecan 150 mg/m2 while UGT1A1*28/*28 received either irinotecan 75 mg/m2 (closed circles) or 100 mg/m2 (diamonds).