Table 3.
Subacute effect of Lavandula stoechas essential oils on acute aloxan-induced changes in liver and kidney functions
|
Glucose |
ALT |
AST |
ALP |
LDH |
Albumin |
Urea |
Uric acid |
Creatinin |
|
|---|---|---|---|---|---|---|---|---|---|
| (mM) | (UI/L) | (UI/L) | (UI/L) | (U/L) | (g/dl) | (mmol/L) | (mmol/L) | (μmol/L) | |
|
Healthy control |
6.65 ± 0.66 |
23 ± 1.59 |
39 ± 2.82 |
129 ± 7.1 |
938 ± 16 |
4.72 ± 0.93 |
7.64 ± 0.38 |
0.28 ± 0.01 |
114 ± 6.7 |
|
Diabetic control |
15.29 ± 1.1
a
|
63 ± 1.38
a
|
68 ± 2.13
a
|
179 ± 6.5
a
|
1246 ± 24
a
|
3.15 ± 0.96
a
|
10.8 ± 0.40
a
|
0.13 ± 0.02
a
|
163 ± 5.9
a
|
|
Healthy + essential oils |
5.17 ± 0.6
b
|
21 ± 1.75
b
|
37 ± 3.63
b
|
148 ± 6.8
b
|
916 ± 13
b
|
5.34 ± 0.30
b
|
7.14 ± 0.35
b
|
0.28 ± 0.01
b
|
126 ± 6.3
b
|
| Diabetic + essential oils | 7.81 ± 0.71 b | 32 ± 1.37 b | 43 ± 2.51 b | 155 ± 9.6 | 1095 ± 38 b | 4.13 ± 0.35 b | 7.21 ± 0.89 | 0.29 ± 0.01 b | 119 ± 8.4 b |
Animals were treated during 15 days with Lavandula stoechas essential oils (50 mg/kg b.w., i.p.) or vehicle (NaCl 0.9%) seven days after diabetic induction with alloxan at 220 mg/kg b.w.. Assays were carried out in triplicate.
a p < 0.05 compared to “Healthy Control” group and b p < 0.05 compared to “Diabetic Control” group.