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. Author manuscript; available in PMC: 2014 Nov 21.
Published in final edited form as: Chem Biol. 2013 Nov 7;20(11):10.1016/j.chembiol.2013.09.018. doi: 10.1016/j.chembiol.2013.09.018

FIGURE 4.

FIGURE 4

Carbonic anhydrase II (CA II) and glutamine synthetase (GS) expression level changes (A) Expression-level analysis of CA II and GS in 12 month-old YAC128 and WT littermate whole brain homogenates. An immunoblot analysis identical to that in Fig. 1C was employed (WT, n=2; YAC128, n=4). (B) Brain distribution of CA II and GS expression reductions. Homogenates from striatum, cortex and cerebellum dissected from five 15 month-old YAC128 and WT littermate brains were subjected to quantitative immunoblot analysis. Results are depicted as means +/− SD. Significance: * P < 0.05, ** P < 0.01, *** P < 0.001.