Table IV.

Factors associated with failure to normalize postoperative calcitonin

Variable	Odds ratio (CI)	Univariate P value	Adjusted OR (CI)	Adjusted P value
Lymph node positivity*	9.4 (3.5–24.9)	<.0001
Number of positive lymph nodes†	2.0 (1.3–3.1)	.001
Tumor size* (cm)	1.9 (1.3–2.9)	<.001
TNM stage	2.7 (1.8–4.0)	<.0001	2.9 (1.4–6.2)	.005
Extent of surgery	2.1 (1.3–3.3)	.002		.34
Preoperative calcitonin‡	1.05 (1.01–1.09)	.026	1.04 (1.00–1.08)	.04

^*Excluded on multivariable analysis because of colinearity with TNM stage.

^†Odds ratio quoted per increments of 5 lymph nodes.

^‡Odds ratio quoted per increments of 500 pg/mL.

CI, Confidence interval.