Table 3. The β-catenin staining pattern, number of tumor associated macrophages (TAMs) and expression (IOD, Integrated Optical Density) of Wnt-2, Wnt-5a, Dkk-1 and ROR-2 in canine mammary metastatic and non-metastatic tumors.
B-catenin staining pattern | metastatic tumors | non-metastatic tumors |
Nucear | N = 5 | |
nucelear+cytoplasmic | N = 13 | |
nucear+cytoplasmic+membranous | N = 5 | |
cytoplasmic+membranous | N = 2 | N = 2 |
cytoplasmic | N = 23 | |
Number of TAMs | 115 (±10) | 80 (±8) |
IOD of Wnt-2 | 550,000 (±8,663) | 181,750 (±120,550) |
IOD of Wnt-5a | 511,300 (±201,236) | 109,284 (±5,352) |
IOD of Dkk-1 | 174,456 (±50,231) | 85,053 (±31,837) |
IOD of ROR-2 | 516,667 (±125,831) | 233,333 (±76,376) |