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. 2014 Jan 3;9(1):e83955. doi: 10.1371/journal.pone.0083955

Figure 8. Effect of EVs from MDA-MB-468 on stem cell and EMT markers in U2OS cells.

Figure 8

U2OS cells were incubated with 0 or 50 µg/mL of MDA-MB-468-derived EVs and quantitative polymerase chain reaction analysis was conducted to examine the expression of the transcription factors Nanog, Oct-4, Sox2, Zeb1 and Snaill involved in development and maintenance of stem cells [data are mean ±SD; n = 3, p<0.05, 0.05, 0.01, 0.05 and 0.01, respectively, relative to the values in the control].