. 2014 Jan 3;9(1):e85188. doi: 10.1371/journal.pone.0085188

Table 2. Effects of coexpression with the β1 subunit on the kinetics of sodium current activation and inactivation and amplitudes of persistent currents in HEK293 cells expressing Na_v1.6 sodium channels.

	Peak current activation and inactivation^a			Persistent current^b
Channel	time to peak	τ_inact	n	percent of peak	n
Na_v1.6	1.00±0.03	1.38±0.05	63	1.48±0.17	64
Na_v1.6β1	0.99±0.02	1.20±0.03^c	60	1.45±0.10	65

^a Time to peak current (ms) and first-order time constant (τ_inact, ms) of sodium current inactivation; values are means ± SE for the indicated number of replicate experiments with different cells.

^b Current measured at the end of a 40-ms depolarizing pulse expressed as a percentage of the peak current in the same depolarization; values are means ± SE for the indicated number of replicate experiments with different cells.

^c Significantly different from the value for Na_v1.6 channels (P<0.005).

Table 2. Effects of coexpression with the β1 subunit on the kinetics of sodium current activation and inactivation and amplitudes of persistent currents in HEK293 cells expressing Nav1.6 sodium channels.

Table 2. Effects of coexpression with the β1 subunit on the kinetics of sodium current activation and inactivation and amplitudes of persistent currents in HEK293 cells expressing Na_v1.6 sodium channels.