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. 2014 Jan 3;9(1):e85188. doi: 10.1371/journal.pone.0085188

Table 3. Effects of coexpression with the β1 subunit on the voltage dependence of activation and steady-state inactivation of Nav1.6 sodium channels expressed in HEK293 cells.a .

Activation Inactivation
Channel V0.5 K n V0.5 K n
Nav1.6 −35.2±0.8 4.19±0.17 64 −68.7±0.7 6.50±0.10 63
Nav1.6β1 −28.6±0.8**b 4.90±0.12** 65 −63.5±0.8* 6.11±0.08** 66

a Values are means ± SE calculated from fits of the data from the indicated number of individual cells to the Boltzmann equation; V0.5, midpoint potential (mV) for voltage-dependent activation or inactivation; K, slope factor.

b Significantly different from the value for Nav1.6 channels (*P<0.001; **P<0.0005).