Table 1.
Physiologic and Laboratory Parameters
| Groups | ||||
|---|---|---|---|---|
| Control (n=6) | Decompensated Shock (n=6) | Severe Shock (n=6) | Resuscitation (n=6) | |
| MAP (mmHg) | 112 ± 5 | 39 ± 2 § | 41 ± 1 § | 78 ± 11 § |
| HR (bpm) | 447 ± 28 | 506 ± 26 § | 419 ± 19 | 438 ± 56 |
| pH | 7.39 ± 0.03 | 7.10 ± 0.19 | 7.05 ± 0.21 | 7.20 ± 0.11 § |
| Lactate (mmol/L) | 1.6 ± 0.9 | 16.0 ± 1.3 § | 17.2 ± 3.1 § | 10.2 ± 3.0 § |
| pCO2 (mmHg) | 50.9 ± 6.3 | 13.8 ± 5.3 § | 16.6 ± 4.8 § | 28.2 ± 3.4 § |
| pO2 (mmHg) | 84.1 ± 9.3 | 113.5 ± 16.5 § | 127.83 ± 9.4 § | 113.17 ± 13.0 § |
| HCO3− (mmol/L) | 30.8 ± 3.0 | 4.3 ± 1.5 § | 5.4 ± 3.8 § | 11.3 ± 2.8 § |
| Base Excess (mmol/L) | 7.2 ± 1.5 | −25.0 ± 3.7 § | −24.7 ± 6.3 § | −16.7 ± 4.6 § |
| O2Sat (%) | 96 ± 1 | 96 ± 2 | 97 ± 1 | 97 ± 1 |
| BUN (mg/dL) | 22.3 ± 3.1 | 27.2 ± 4.0 | 29.3 ± 3.8 * | 25.3 ± 3.2 |
| Creatinine (mg/dL) | 0.3 ± 0.1 | 0.5 ± 0.1 § | 0.6 ± 0.1 § | 0.5 ± 0.1 § |
| Alanine Aminotransferase (u/L) | 70.3 ± 11.4 | 54.7 ± 11.3 § | 61.2 ± 10.6 | 145.3 ± 47.1 § |
| Aspartate Aminotransferase (u/L) | 90.0 ± 44.0 | 66.7 ± 17.4 | 68.2 ± 21.8 | 241.3 ± 105.5 § |
| Na+ (mmol/L) | 135.2 ± 3.0 | 129.3 ± 2.2 | 128.2 ± 2.7 * | 130.3 ± 6.1 |
| K+ (mmol/L) | 4.4 ± 0.5 | 6.8 ± 0.9 § | 6.4 ± 1.4 | 5.0 ± 0.6 |
| Cl− (mmol/L) | 102.3 ± 1.8 | 101.8 ± 2.6 | 101.2 ± 1.9 | 100.3 ± 4.3 |
| Hb (g/dL) | 12.3 ± 1.0 | 6.5 ± 2.3 § | 5.0 ± 1.2 § | 3.8 ± 0.3 § |
Data was analyzed using ANOVA with * and § representing significance of p<0.05 and p<0.005 respectively compared to baseline values. Data is represented as mean ± SD.